Frequently Asked Questions

Yes. In November 2022, Colorado voters passed Proposition 122, also known as the Natural Medicine Health Act. This landmark legislation created a regulated framework for the therapeutic use of certain natural medicines, including psilocybin and psilocin (the active compounds found in certain species of mushrooms). Under this law, licensed facilitators can legally guide clients through psychedelic experiences in approved settings. Peak Psychedelic Wellness operates fully within this legal framework, ensuring that every session is compliant with Colorado state regulations.

When administered in a controlled, therapeutic setting with proper screening and professional guidance, psilocybin therapy has demonstrated a strong safety profile. Clinical trials conducted at institutions such as Johns Hopkins University, NYU, and Imperial College London have consistently found that psilocybin produces few serious adverse effects when used under supervised conditions. At Peak Psychedelic Wellness, safety is our highest priority. Every client undergoes a thorough screening process, and all sessions are guided by trained, licensed professionals in a carefully prepared environment.

As with any therapeutic intervention, there are potential side effects to be aware of. During a psilocybin session, some individuals may experience nausea, elevated heart rate, emotional intensity, or temporary anxiety. These effects are typically short-lived and manageable with proper support. Serious adverse events are rare in clinical settings. Our thorough screening process helps identify individuals for whom psychedelic therapy may not be appropriate, and our facilitators are trained to provide support throughout the entire experience.

Our practice centers on psilocybin, the naturally occurring psychoactive compound found in certain species of mushrooms. Psilocybin has been the subject of extensive clinical research and has received Breakthrough Therapy designation from the U.S. Food and Drug Administration (FDA) for treatment-resistant depression. We use only natural psilocybin products that comply with Colorado’s Natural Medicine Health Act.

Our approach follows a well-established three-phase model used in clinical research worldwide: preparation, session, and integration. During the preparation phase, we work with you to establish goals, address any concerns, and ensure you feel safe and supported. The psychedelic session itself takes place in a comfortable, controlled environment with a trained facilitator present throughout. Afterward, integration sessions help you process your experience and translate insights into meaningful, lasting changes in your daily life.

Preparation is a critical part of the therapeutic process. Before your session, you will participate in one or more preparation meetings where we discuss your intentions, review what to expect during the experience, and address any questions or concerns. We also provide guidance on practical preparations, such as dietary recommendations, sleep, and mindset. Our goal is to ensure you feel informed, comfortable, and ready to engage fully with the experience.

Integration is the process of making sense of your psychedelic experience and applying its insights to your everyday life. Research shows that the therapeutic benefits of psilocybin are significantly enhanced when paired with professional integration support. During integration sessions, we help you reflect on your experience, identify key themes and insights, and develop actionable steps for continued growth. Many experts consider integration to be the most important phase of psychedelic therapy, as it bridges the gap between a powerful experience and lasting, meaningful change.

A psilocybin session typically lasts between four and six hours, depending on the individual and the dosage used. We recommend setting aside a full day for your session to allow for arrival, preparation, the experience itself, and a period of rest afterward. You should not plan to drive or engage in demanding activities for the remainder of the day following your session.

Research has shown promising results for psilocybin-assisted therapy in treating a range of mental health conditions, including treatment-resistant depression, post-traumatic stress disorder (PTSD), anxiety disorders, obsessive-compulsive disorder (OCD), and end-of-life distress. Beyond clinical conditions, many individuals also seek psychedelic therapy for personal growth, enhanced self-awareness, and greater emotional resilience. During your initial consultation, we will discuss your specific needs and goals to determine whether psychedelic therapy may be a good fit for you.

Psychedelic therapy is not appropriate for everyone. Individuals with a personal or family history of psychotic disorders (such as schizophrenia or bipolar disorder with psychotic features) are generally advised against using psilocybin, as it may exacerbate these conditions. People with certain cardiovascular conditions, those who are pregnant, or individuals taking specific medications (such as lithium) may also be contraindicated. Our screening process is designed to identify any factors that may make psychedelic therapy unsuitable, ensuring the safety and well-being of every client.

No. You do not need a referral from a physician or a formal diagnosis to explore psychedelic therapy at Peak Psychedelic Wellness. Our services are available to adults who are seeking support for mental health concerns or personal growth. However, we do conduct a thorough intake process to ensure that psychedelic therapy is safe and appropriate for each individual.

The number of sessions varies based on individual needs and goals. Some clients experience meaningful shifts after a single session, while others benefit from a series of sessions over time. During your initial consultation, we will work with you to develop a personalized plan that aligns with your therapeutic goals. Most protocols include preparation sessions before and integration sessions after each psychedelic experience.

At this time, most insurance plans do not cover psilocybin-assisted therapy, as psilocybin has not yet received full FDA approval. However, the landscape is evolving rapidly. We are committed to making our services as accessible as possible and can discuss pricing and payment options during your initial consultation. Some clients may be able to use Health Savings Accounts (HSAs) or Flexible Spending Accounts (FSAs), depending on their plan.

We are located in the Denver Tech Center in Greenwood Village, Colorado. Our facility is designed to provide a safe, comfortable, and calming environment for your psychedelic therapy experience. Specific address details and directions will be provided when you schedule your appointment.

The scientific evidence supporting psilocybin therapy has grown substantially in recent years. Landmark studies from Johns Hopkins University, Imperial College London, and NYU Langone Health have demonstrated that psilocybin-assisted therapy can produce rapid and sustained improvements in depression, anxiety, and PTSD symptoms. In 2018 and 2019, the FDA granted Breakthrough Therapy designation to psilocybin for treatment-resistant depression and major depressive disorder, signaling its recognition of the compound’s therapeutic potential. Research published in peer-reviewed journals such as The New England Journal of Medicine, JAMA Psychiatry, and The Lancet Psychiatry continues to strengthen the evidence base for this approach.

Psilocybin works primarily by activating serotonin receptors in the brain, particularly the 5-HT2A receptor. This activation leads to increased communication between brain regions that do not typically interact, a phenomenon researchers describe as enhanced neural connectivity. Brain imaging studies have shown that psilocybin temporarily reduces activity in the default mode network (DMN), a brain network associated with self-referential thinking and rumination. This reduction in DMN activity is believed to be one mechanism through which psilocybin helps break rigid patterns of thought associated with depression, anxiety, and other mental health conditions. The result is often described as a temporary increase in cognitive flexibility, allowing individuals to see their challenges from new perspectives.

No. Psilocybin is not considered addictive, and research consistently supports this finding. Unlike substances such as opioids, alcohol, or nicotine, psilocybin does not produce compulsive drug-seeking behavior, physical dependence, or withdrawal symptoms. In fact, studies have shown that psilocybin may actually help treat substance use disorders, including alcohol and tobacco dependence. The compound produces rapid tolerance, meaning that repeated use in a short timeframe leads to diminished effects, which naturally discourages frequent use.